Carbohydrate-derived amino-alcohol ligands for asymmetric alkynylation of aldehydes.

نویسندگان

  • Daniel P G Emmerson
  • William P Hems
  • Benjamin G Davis
چکیده

[reaction: see text] Conformationally restricted amino alcohols based on carbohydrate scaffolds provide flexible and fine-tuneable libraries that greatly expand the range of ligands available in the Zn(OTf)(2)-mediated addition of alkynes to aldehydes, in some cases with very high stereoselectivities.

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عنوان ژورنال:
  • Organic letters

دوره 8 2  شماره 

صفحات  -

تاریخ انتشار 2006