Carbohydrate-derived amino-alcohol ligands for asymmetric alkynylation of aldehydes.
نویسندگان
چکیده
[reaction: see text] Conformationally restricted amino alcohols based on carbohydrate scaffolds provide flexible and fine-tuneable libraries that greatly expand the range of ligands available in the Zn(OTf)(2)-mediated addition of alkynes to aldehydes, in some cases with very high stereoselectivities.
منابع مشابه
Readily available sulfamide-amine alcohols for enantioselective phenylacetylene addition to aldehydes in the absence of Ti(O(i)Pr)4.
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عنوان ژورنال:
- Organic letters
دوره 8 2 شماره
صفحات -
تاریخ انتشار 2006